Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453211 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1ALOX12KCNH2 | |
| SCHEMBL20847994 | 0.86 | NPC1 (0.73) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL5450344 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1ALOX12KCNH2 | |
| SCHEMBL1514749 | 0.84 | RAB9A (0.65) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL28892777 | 0.80 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL5443694 | 0.79 | MITF (0.63) | ALDH1A1KMT2AMEN1ALOX12CYP2C19 | |
| SCHEMBL3054964 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1ALOX12CYP1A2 | |
| SCHEMBL27446979 | 0.76 | NPC1 (0.75) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL1337541 | 0.76 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1ALOX12MAPT | |
| SCHEMBL5453761 | 0.76 | KMT2A (0.78) | ALDH1A1KMT2AMEN1ALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |