Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443855 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2ANPC1POLBALDH1A1 | |
| SCHEMBL27422 | 0.82 | TSHR (0.60) | TAS2R14PLK1ALDH1A1ALOX15TSHR | |
| SCHEMBL5443841 | 0.81 | MAPT (0.47) | MEN1KMT2ANPC1POLBALDH1A1 | |
| SCHEMBL27890905 | 0.80 | TSHR (0.57) | TAS2R14PLK1ALDH1A1ALOX15TSHR | |
| SCHEMBL5436479 | 0.77 | BCL2L1 (0.57) | TAS2R14MEN1KMT2ANPC1POLB | |
| SCHEMBL5445817 | 0.77 | CA1 (0.67) | TAS2R14NPC1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL2707464 | 0.76 | HPGD (0.56) | TAS2R14PLK1ALDH1A1TSHRTP53 | |
| SCHEMBL3640502 | 0.76 | HAO1 (0.61) | TAS2R14PLK1ALDH1A1TSHRTP53 | |
| SCHEMBL5445794 | 0.75 | KMT2A (0.49) | TAS2R14MEN1KMT2ANPC1POLB | |
| SCHEMBL1548149 | 0.75 | TRPA1 (0.62) | TAS2R14MEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | claimed |
| EP-1687260-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GmbH (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051896-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | TAS2R14 3162/4885MEN1 2301/4885KMT2A 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.