SCHEMBL544597

SCHEMBL544597

CCCCCCCC(CCC[Si](OCC)(OCC)OCC)SSC(CCCCCCC)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
LMNA P02545 2/20 0.33
DNM1 Q05193 1/20 0.30
SMPD1 P17405 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28695301 0.83
SCHEMBL11314998 0.82 OPRM1 (0.33) OPRM1LMNADNM1SMPD1
SCHEMBL5575534 0.80 OPRM1 (0.34) OPRM1LMNADNM1SMPD1
SCHEMBL30692473 0.80 OPRM1 (0.34) OPRM1LMNADNM1SMPD1
SCHEMBL16538101 0.78 TSHR (0.42) LMNADNM1
SCHEMBL6534000 0.78 TSHR (0.42) LMNADNM1
Octane SCHEMBL18660174 0.78 TSHR (0.42) LMNADNM1
SCHEMBL28138 0.78 TSHR (0.42) LMNADNM1
SCHEMBL21456807 0.78 TSHR (0.42) LMNADNM1
SCHEMBL818646 0.78 TSHR (0.42) LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066539-B2 Rubber composition KAO CORPORATION (JP) 2021-07-20 US disclosed
US-10717852-B2 Additive for resins KAO CORPORATION (JP) 2020-07-21 US disclosed
US-20200048438-A1 RUBBER COMPOSITION KAO CORPORATION (JP) 2020-02-13 US disclosed
EP-3299412-B1 ADDITIVE FOR RESINS KAO CORP (JP) 2019-07-31 EP disclosed
US-20180142088-A1 ADDITIVE FOR RESINS KAO CORPORATION (JP) 2018-05-24 US disclosed
EP-3299412-A1 ADDITIVE FOR RESINS Kao Corporation (JP) 2018-03-28 EP disclosed
EP-2226354-B1 Rubber composition BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-8110625-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2012-02-07 US disclosed
EP-2223958-B1 Rubber composition BRIDGESTONE CORP (JP) 2011-12-28 EP disclosed
US-20100298488-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2010-11-25 US disclosed
US-7799856-B2 Rubber composition BRIDGESTONE CORPORATION (JP) 2010-09-21 US disclosed
EP-2226354-A1 Rubber composition Bridgestone Corporation (JP) 2010-09-08 EP disclosed
EP-2223958-A1 Rubber composition Bridgestone Corporation (JP) 2010-09-01 EP disclosed
US-20040249032-A1 Rubber composition BRIDGESTONE CORPORATION (JP) 2004-12-09 US disclosed
EP-1435375-A1 RUBBER COMPOSITION Bridgestone Corporation (JP) 2004-07-07 EP disclosed
EP-1081187-B1 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORP (JP) 2004-02-18 EP disclosed
US-6355710-B1 MIXTURE WITH FILLER AND AMINE SALT BRIDGESTONE CORPORATION (JP) 2002-03-12 US disclosed
EP-1081187-A2 Rubber composition containing silica or silicate and salt of an amine BRIDGESTONE CORPORATION (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298488-A1 RUBBER COMPOSITION RAD50, RAD54L, VCL OPRM1 1596/4885LMNA 377/4885DNM1 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.