SCHEMBL4532046

SCHEMBL4532046

C[n+]1c2ccccc2c(C(=O)Oc2ccc(CCC(=O)ON3C(=O)CCC3=O)cc2)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.37
PSMB8 P28062 1/20 0.36
PSMB5 P28074 1/20 0.36
HPGD P15428 2/20 0.35
CASP3 P42574 1/20 0.34
CASP7 P55210 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 1/20 0.33
PTGS2 P35354 1/20 0.33
FFAR1 O14842 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666930 1.00 KMT2A (0.37) KMT2APSMB8PSMB5HPGDCASP3
SCHEMBL374354 0.94 KMT2A (0.33) KMT2APSMB8PSMB5HPGDCASP3
SCHEMBL7517352 0.93 LMNA (0.35) KMT2APSMB8PSMB5HPGDCASP3
Trifluoromethanesulfonic Acid SCHEMBL12096566 0.91 PSMB8 (0.32) KMT2APSMB8PSMB5HPGDSMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL29698948 0.91 PSMB8 (0.32) KMT2APSMB8PSMB5HPGDSMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL2225877 0.85 PSMB8 (0.32) KMT2APSMB8PSMB5SMN1; SMN2MAPT
SCHEMBL31165787 0.85 KMT2A (0.36) KMT2APSMB8PSMB5HPGDCASP3
SCHEMBL9426644 0.84 PSMB8 (0.32) PSMB8PSMB5
SCHEMBL1073436 0.82 KMT2A (0.36) KMT2AHPGDCASP3CASP7SMN1; SMN2
SCHEMBL9322067 0.79 PPARG (0.42) KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240077489-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. 2024-03-07 US disclosed
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 US disclosed
US-20230272457-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE ILLUMINA, INC. 2023-08-31 US disclosed
US-11629373-B2 Compositions, systems, and methods for detecting the presence of polymer subunits using chemiluminescence ILLUMINA, INC. (US) 2023-04-18 US disclosed
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2022-02-01 US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 US disclosed
US-20200318167-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE ILLUMINA, INC. 2020-10-08 US disclosed
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. 2020-06-04 US disclosed
EP-3191606-B1 METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE ILLUMINA INC (US) 2020-05-27 EP disclosed
US-10633694-B2 Compositions, systems, and methods for detecting the presence of polymer subunits using chemiluminescence ILLUMINA, INC. (US) 2020-04-28 US disclosed
US-20090298062-A1 METHOD FOR DETERMINATION OF THE LENGTH OF THE G-TAIL SEQUENCE AND KIT FOR THE METHOD HIROSHIMA UNIVERSITY (JP) 2009-12-03 US disclosed
US-20090298062-A1 METHOD FOR DETERMINATION OF THE LENGTH OF THE G-TAIL SEQUENCE AND KIT FOR THE METHOD HIROSHIMA UNIVERSITY (JP) 2009-12-03 US disclosed
EP-1935989-A1 METHOD FOR DETERMINATION OF THE LENGTH OF G-TAIL SEQUENCE AND KIT FOR THE METHOD Hiroshima University (JP) 2008-06-25 EP disclosed
EP-0082636-B2 Luminescent labelling materials and procedures WELSH NAT SCHOOL OF MEDICINE (GB) 2006-10-18 EP disclosed
US-7122671-B1 Luminescent labelling materials and procedures UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2006-10-17 US disclosed
US-20040235138-A1 Compositions, methods and kits for determining the presence of Trichomonas vaginalis in a test sample BIOLUCENT, LLC 2004-11-25 US disclosed
US-6414152-B1 COMPOUND CAPABLE OF UNDERGOING LIGHT EMITTING REACTION IN PRESENCE OF DILUTE SOLUTION OF SODIUM HYDROXIDE AND HYDROGEN PEROXIDE, COMPRISING ACRIDINIUM CARBONYL MOIETY SUBSTITUTED WITH ARYL MOIETY HAVING ATTACHED REACTIVE GROUP UNIVERSITY OF WALES COLLEGE OF MEDICINE OF HEATH PARK (GB) 2002-07-02 US disclosed
US-5093270-A Chemiluminescence of acridinium esters CIBA CORNING DIAGNOSTICS CORP. (US) 1992-03-03 US disclosed
US-4946958-A Chemiluminescent acridinium labelling compounds THE WELSH NATIONAL SCHOOL OF MEDICINE (GB) 1990-08-07 US disclosed
EP-0082636-B1 LUMINESCENT LABELLING MATERIALS AND PROCEDURES The Welsh National School of Medicine (GB) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS KMT2A 3324/4885PSMB8 2638/4885PSMB5 3676/4885
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS KMT2A 3324/4885PSMB8 2638/4885PSMB5 3676/4885
US-20240077489-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS KMT2A 3324/4885PSMB8 2638/4885PSMB5 3676/4885
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS KMT2A 3324/4885PSMB8 2638/4885PSMB5 3676/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS KMT2A 3324/4885PSMB8 2638/4885PSMB5 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.