Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL28158541 | 0.84 | KIF11 (0.44) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4395392 | 0.81 | MAPT (0.61) | GAANPSR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5463340 | 0.81 | IDO1 (0.61) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL650677 | 0.81 | KIF11 (0.48) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3421577 | 0.81 | ALDH1A1 (0.63) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4391461 | 0.81 | HPGD (0.62) | KMT2AMEN1CYP1A2CYP2C19HTT | |
| SCHEMBL166139 | 0.80 | KIF11 (0.55) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1278440 | 0.80 | ALDH1A1 (0.61) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1276739 | 0.80 | KMT2A (0.79) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL11844402 | 0.79 | KIF11 (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |