SCHEMBL650677

SCHEMBL650677

Cc1ccc(NC(=N)NC(=N)N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.48
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
TDP1 Q9NUW8 1/20 0.45
DDAH1 O94760 1/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11844402 0.98 KIF11 (0.47) KIF11GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL21530444 0.98 KIF11 (0.47) KIF11GRIN2DGRIN3BGRIN1GRIN2A
Ethylene SCHEMBL7172674 0.96 KIF11 (0.46) KIF11GRIN2DGRIN3BGRIN1GRIN2A
Thiourea SCHEMBL28158541 0.94 KIF11 (0.44) KIF11GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3068902 0.89 F2 (0.43) MAPTNPC1RAB9ACYP3A4CYP2C19
Metformin SCHEMBL28092112 0.88 KIF11 (0.40) KIF11GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3056662 0.87 TDP1 (0.52) KIF11GRIN2DGRIN3BGRIN1GRIN2A
Butanal SCHEMBL28107659 0.83 DDAH1 (0.40) KIF11GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL166139 0.83 KIF11 (0.55) KIF11GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL678436 0.83 TDP1 (0.56) KIF11GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 855 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820819-A Electronic grade weather-resistant epoxy resin composition, and preparation method and application thereof 安徽美佳新材料股份有限公司 2024-04-05 CN claimed
CN-113908696-A Method for preparing reverse osmosis membrane and reverse osmosis membrane prepared thereby 沃顿科技股份有限公司 2022-01-11 CN claimed
EP-3898263-A1 RUBBER COMPOSITION COMPRISING A POLYSULFIDE COMPOUND COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-27 EP claimed
WO-2020128260-A1 RUBBER COMPOSITION COMPRISING A POLYSULFIDE COMPOUND COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-06-25 WO claimed
CN-110615886-A Biguanide derivative antibacterial epoxy resin curing agent and preparation method thereof 哈尔滨工程大学 2019-12-27 CN claimed
CN-105408126-B Process for producing rubber compounds for tyres 株式会社普利司通 2017-09-29 CN claimed
CN-105377576-B The manufacture method of rubber for tire mixing material 株式会社普利司通 2017-07-28 CN claimed
CN-106795295-A The manufacture method of rubber composition 株式会社普利司通 2017-05-31 CN claimed
CN-103588958-B Mixtures of amines having guanidine derivatives 巴斯夫欧洲公司 2017-01-18 CN claimed
EP-3065831-A1 SEMI-PERMANENT HAIR STRAIGHTENING COMPOSITION AND METHOD Lubrizol Advanced Materials, Inc. (US) 2016-09-14 EP claimed
CN-101395013-B Tyre and crosslinkable elastic composition PIRELLI TYRES CO LTD 2010-07-21 CN claimed
CN-1730725-B Surface treatment method for flux-brazed aluminum-made heat exchanger NIPPON PAINT CO LTD 2010-06-23 CN claimed
CN-101395013-A Tyre and crosslinkable elastic composition PIRELLI TYRES CO LTD (IT) 2009-03-25 CN claimed
CN-101056936-A Amphiphilic block copolymer-toughened epoxy resins and powder coatings made therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2007-10-17 CN claimed
WO-2007062853-A1 USE OF 1-(N'-CYANOGUANYL) DERIVATES OF N-CONTAINING FIVE-MEMBERED HETEROCYCLIC RINGS AS HARDENERS FOR EPOXY RESIN COMPOSITIONS ALZCHEM TROSTBERG GMBH (DE) 2007-06-07 WO claimed
CN-1269819-A Food cleaning compositions containing cyclodextrin PROCTER & GAMBLE (US) 2000-10-11 CN claimed
WO-1999055815-A1 IMPROVED UNCOMPLEXED CYCLODEXTRIN COMPOSITIONS FOR ODOR CONTROL THE PROCTER & GAMBLE COMPANY (US) 1999-11-04 WO claimed
WO-1995027761-A1 POWDER COMPOSITION FOR COATINGS MACHLIAKOVSKI LEONID NIKOLAYEV (RU) 1995-10-19 WO claimed
EP-0366608-B1 Powder coating useful as a mat coating CIBA GEIGY AG (CH) 1993-12-15 EP claimed
EP-0366608-A2 Powder coating useful as a mat coating CIBA-GEIGY AG (CH) 1990-05-02 EP claimed