SCHEMBL5447128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5456366	0.89	FLT3 (0.52)	FLT3GRIN2CNPC1RAB9ACDC7
	SCHEMBL5447561	0.84	FLT3 (0.43)	FLT3GRIN2CNPC1RAB9ACDC7
	SCHEMBL5460181	0.83	GRIN2C (0.44)	FLT3GRIN2CNPC1RAB9ACDC7
	SCHEMBL5466113	0.83	FLT3 (0.42)	FLT3GRIN2CNPC1RAB9AMEN1
	SCHEMBL5447136	0.83	FLT3 (0.44)	FLT3GRIN2CNPC1RAB9ACDC7
	SCHEMBL5460130	0.83	FLT3 (0.42)	FLT3GRIN2CNPC1RAB9ACDC7
	SCHEMBL5455924	0.80	FLT3 (0.54)	FLT3GRIN2CNPC1RAB9AMEN1
	SCHEMBL5453155	0.80	TAS1R3 (0.43)	FLT3NPC1RAB9AMAPTSMN1; SMN2
	SCHEMBL5458431	0.77	FLT3 (0.45)	FLT3NPC1RAB9AMEN1KMT2A
	SCHEMBL5450952	0.77	RHOC (0.42)	FLT3GRIN2CKDRMAP4K5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.