Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442604 | 0.82 | ALDH1A1 (0.47) | ALOX15ALDH1A1TAS2R14TSHRNPC1 | |
| SCHEMBL5440855 | 0.82 | ALDH1A1 (0.47) | ALOX15ALDH1A1TAS2R14RXRARXRB | |
| SCHEMBL5443855 | 0.82 | ALDH1A1 (0.56) | ALOX15ALDH1A1TSHRNPC1SRD5A2 | |
| SCHEMBL5440611 | 0.81 | ALDH1A1 (0.46) | ALOX15ALDH1A1TSHRNPC1SRD5A2 | |
| SCHEMBL5442747 | 0.79 | ALDH1A1 (0.43) | ALOX15ALDH1A1TSHRRAB9APTPRC | |
| SCHEMBL5449085 | 0.78 | ALDH1A1 (0.43) | ALOX15ALDH1A1TAS2R14NPC1MEN1 | |
| SCHEMBL5450787 | 0.78 | ALDH1A1 (0.46) | ALOX15ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL5447510 | 0.76 | ALDH1A1 (0.47) | ALOX15ALDH1A1NR4A2MEN1KMT2A | |
| SCHEMBL5445995 | 0.76 | NR3C1 (0.44) | ALOX15ALDH1A1TSHRRAB9AMEN1 | |
| SCHEMBL5443841 | 0.74 | MAPT (0.47) | ALOX15ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | claimed |
| EP-1687260-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GmbH (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051896-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | ALOX15 599/4885ALDH1A1 365/4885TAS2R14 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.