SCHEMBL5447262

SCHEMBL5447262

N#CCCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
NAAA Q02083 1/20 0.47
MAOB P27338 2/20 0.44
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
IDO1 P14902 1/20 0.41
LTA4H P09960 1/20 0.41
CTSL P07711 2/20 0.41
CTSB P07858 2/20 0.41
CTSK P43235 2/20 0.41
CHRM3 P20309 2/20 0.40
GUSB P08236 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AGXT P21549 1/20 0.40
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27837369 0.94 TSHR (0.50) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL26813025 0.93 TSHR (0.48) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL26812996 0.93 TSHR (0.48) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL3648830 0.88 TSHR (0.52) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL10970522 0.86 TSHR (0.50) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL23227828 0.86 TSHR (0.45) TSHRNAAAMAOBCYP3A4CYP2C9
SCHEMBL9543167 0.85 L3MBTL1 (0.50) TSHRNAAAMAOBCTSLCTSB
SCHEMBL20641675 0.85 L3MBTL1 (0.50) TSHRNAAAMAOBCTSLCTSB
SCHEMBL28088501 0.84 TSHR (0.40) TSHRNAAACTSLCTSBCTSK
Biphenyl SCHEMBL27837456 0.83 NAAA (0.51) TSHRNAAAMAOBIDO1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111056963-B Preparation method of 3-aminopropanol 山东新和成精化科技有限公司 2022-12-16 CN claimed
CN-111056963-A Preparation method of 3-aminopropanol 山东新和成精化科技有限公司 2020-04-24 CN claimed
US-4657558-A Method for continuous dyeing polyester pile fabrics: aromatic nitrile ether or oxyethylated chlorophenol fixing accelerator COLLINS & AIKMAN CORPORATION (US) 1987-04-14 US claimed
US-4297103-A Process for the continuous one-bath dyeing of pile fabrics made of polyacrylonitrile/cotton BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US claimed
CN-116102437-B Preparation method of 3-aminopropanol 南京红宝丽醇胺化学有限公司 2025-03-04 CN disclosed
CN-112261970-B 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family zinc finger 2 (IKZF 2) dependent diseases 诺华股份有限公司 2025-02-07 CN disclosed
CN-119365502-A Polymer emulsion, and one-part thermosetting resin composition, two-part thermosetting resin composition, paint, resin cured film, and coating film using the same 株式会社力森诺科 2025-01-24 CN disclosed
CN-119241499-A 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof 诺华股份有限公司 2025-01-03 CN disclosed
CN-119219511-A Preparation method of 3-aminopropanol and preparation method of D-panthenol 浙江新和成股份有限公司 2024-12-31 CN disclosed
CN-114144438-B Method for producing acrylate rubber 株式会社大阪曹達 2024-08-02 CN disclosed
CN-116874381-A Preparation method of 3-aminopropanol 万华化学集团股份有限公司 2023-10-13 CN disclosed
CN-116102437-A Preparation method of 3-aminopropanol 南京红宝丽醇胺化学有限公司 2023-05-12 CN disclosed
EP-0019702-A2 Distyrylebiphenyles, process for their preparation and their use for the optical brightening of organic materials, as well as detergent compositions, textile treating compositions and products for the after-treatment of laundry containing them CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
EP-0019078-A2 Distyrylebenzenes,process for their preparation and their use for the optical brightening of organic materials,as well as detergent compositions, textile treating compositions and products for the after-treatment of laundry containing such distyrylbenzenes CIBA-GEIGY AG (CH) 1980-11-26 EP disclosed
US-4233214-A FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-11-11 US disclosed
US-4201707-A Methine dyestuffs containing a phenyl azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4143228-A RED SHADES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4070500-A KETONE RESIN, EXTENDER MILLMASTER ONYX CORPORATION (US) 1978-01-24 US disclosed
US-4036826-A Cationic azo dyestuffs with a hydroxyalkylated ammonium group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed