Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20641675 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TDP1TSHRLTB4RNAAA | |
| SCHEMBL10970522 | 0.98 | TSHR (0.50) | L3MBTL1TDP1TSHRLTB4RNAAA | |
| SCHEMBL3648830 | 0.93 | TSHR (0.52) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| SCHEMBL26813025 | 0.89 | TSHR (0.48) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| Biphenyl SCHEMBL27837456 | 0.88 | NAAA (0.51) | L3MBTL1TDP1TSHRLTB4RNAAA | |
| SCHEMBL26812996 | 0.86 | TSHR (0.48) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| SCHEMBL5447262 | 0.85 | TSHR (0.56) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| SCHEMBL9011734 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| SCHEMBL9011646 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRNAAAHRH4 | |
| SCHEMBL9011624 | 0.84 | TSHR (0.67) | L3MBTL1TDP1TSHRNAAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12171756-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| CN-111793060-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20220257587-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2022-08-18 | — | — | US | disclosed |
| US-11344543-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3652166-A1 | NLRP3 MODULATORS | Innate Tumor Immunity, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20200129500-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2020-04-30 | — | — | US | disclosed |
| WO-2019014402-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| WO-1993001196-A1 | KETOALKYLGLYCEROPHOSPHOLIPIDS HAVING ANTITUMOR AND ANTI-PLATELET AGGREGATION ACTIVITIES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | LABORATORIOS MENARINI S.A. (ES) | 1993-01-21 | — | — | WO | disclosed |
| US-5066658-A | Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200129500-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, PYCARD | L3MBTL1 3770/4885TDP1 575/4885TSHR 4789/4885 |
| US-20220257587-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, PYCARD | L3MBTL1 3780/4885TDP1 842/4885TSHR 4795/4885 |
| US-11344543-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | L3MBTL1 3770/4885TDP1 575/4885TSHR 4789/4885 |
| US-12171756-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | L3MBTL1 3780/4885TDP1 842/4885TSHR 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.