Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052632 | 0.84 | PTGDR2 (0.54) | PTGS2PTGDR2MEP1BCA2CAMK2A | |
| SCHEMBL168163 | 0.84 | PTGDR2 (0.54) | PTGS2PTGDR2MEP1BCA2CAMK2A | |
| SCHEMBL28288707 | 0.83 | KMT2A (0.51) | PTGS2PTGDR2MEP1BCA2CAMK2A | |
| Hydrochloric Acid SCHEMBL15411526 | 0.82 | PTGDR2 (0.52) | PTGS2PTGDR2MEP1BCA2CAMK2A | |
| SCHEMBL5445794 | 0.80 | KMT2A (0.49) | ALOX5CA2 | |
| SCHEMBL5441097 | 0.78 | CTBP2 (0.47) | PTGDR2CA2CAMK2ANR1H4 | |
| SCHEMBL5447533 | 0.78 | CTBP2 (0.47) | PTGDR2CA2CAMK2ANR1H4 | |
| SCHEMBL5447675 | 0.78 | KDM4E (0.56) | PTGDR2ALOX5KEAP1NFE2L2 | |
| SCHEMBL5463159 | 0.75 | RORC (0.48) | PTGS2PTGDR2MEP1BRORC | |
| SCHEMBL11562112 | 0.75 | SRD5A2 (0.55) | PTGS2PTGDR2MEP1BCA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | claimed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | PTGS2 580/4885PTGDR2 232/4885PTGES 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.