Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052632 | 0.89 | PTGDR2 (0.54) | MEP1BPTGDR2PTGS2GAAKDM4E | |
| SCHEMBL168163 | 0.89 | PTGDR2 (0.54) | MEP1BPTGDR2PTGS2GAAKDM4E | |
| Hydrochloric Acid SCHEMBL15411526 | 0.88 | PTGDR2 (0.52) | MEP1BPTGDR2PTGS2GAAKDM4E | |
| SCHEMBL11562112 | 0.80 | SRD5A2 (0.55) | MEP1BPTGDR2PTGS2GAAKDM4E | |
| SCHEMBL25667539 | 0.80 | ENPP2 (0.54) | GAAMEN1KMT2ATGM2 | |
| SCHEMBL28288707 | 0.79 | KMT2A (0.51) | MEP1BPTGDR2PTGS2MEN1KMT2A | |
| SCHEMBL1422207 | 0.77 | ALDH1A1 (0.63) | CYP26A1CYP26B1GAAKDM4EPOLB | |
| SCHEMBL5464915 | 0.77 | CA1 (0.50) | PTGS2MEN1KMT2ATGM2 | |
| SCHEMBL3245767 | 0.76 | MEN1 (0.58) | PTGS2GAAPOLBMEN1KMT2A | |
| SCHEMBL5455400 | 0.75 | GAA (0.59) | GAAKDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| EP-1687253-A2 | DIPHENYLAMINE DERIVATIVES | Merk Patent Gmbh (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051888-A2 | DIPHENYLAMINE DERIVATIVES | MERK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | RORC 2850/4885MEP1B 3166/4885CYP26A1 515/4885 |
| US-20070129433-A1 | Diphenylamine derivatives | CCNY, CHKB, CHKA | RORC 2643/4885MEP1B 3342/4885CYP26A1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.