Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762137 | 0.89 | MAPT (0.55) | KDM4EMAPTKIF11LMNASMN1; SMN2 | |
| SCHEMBL8128555 | 0.85 | KIF11 (0.61) | KDM4EMAPTKIF11LMNASMN1; SMN2 | |
| SCHEMBL22761944 | 0.83 | MAPT (0.59) | KDM4EMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL22762131 | 0.82 | KDM4E (0.55) | KDM4EMAPTKIF11LMNASMN1; SMN2 | |
| SCHEMBL3837922 | 0.82 | KIF11 (0.53) | KDM4EMAPTKIF11LMNASMN1; SMN2 | |
| SCHEMBL11995709 | 0.82 | PARP1 (0.55) | KDM4EMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL25703698 | 0.81 | KIF11 (0.61) | KDM4EMAPTKIF11LMNASMN1; SMN2 | |
| SCHEMBL29368226 | 0.81 | KIF11 (0.75) | KDM4EKIF11SMN1; SMN2HTTCYP3A4 | |
| SCHEMBL5466693 | 0.81 | KIF11 (0.75) | KDM4EKIF11SMN1; SMN2HTTCYP3A4 | |
| SCHEMBL30914261 | 0.81 | KIF11 (0.75) | KDM4EKIF11SMN1; SMN2HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11056656-B2 | Organoboron complexes and their use in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-07-06 | — | — | US | disclosed |
| EP-3621970-B1 | ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-01-13 | — | — | EP | disclosed |
| US-20200388761-A1 | ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11056656-B2 | Organoboron complexes and their use in organic electroluminescent devices | NDUFC1, MT-ND6, NDUFC2 | KDM4E 4360/4885MAPT 2057/4885KIF11 2352/4885 |
| US-20200388761-A1 | ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES | NDUFC1, KCNC1, MT-ND6 | KDM4E 4218/4885MAPT 2553/4885KIF11 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.