Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930590 | 0.86 | ALDH1A1 (0.43) | ALDH1A1GAAKDM4ETSHRCYP2A6 | |
| SCHEMBL5437608 | 0.81 | PSMB5 (0.46) | ALDH1A1KDM4ETSHRCYP2A6CYP2A13 | |
| SCHEMBL5439295 | 0.81 | PSMB5 (0.46) | ALDH1A1KDM4ETSHRCYP2A6CYP2A13 | |
| SCHEMBL392759 | 0.80 | HSD17B3 (0.51) | ALDH1A1APPTSHRMEN1KMT2A | |
| SCHEMBL28195990 | 0.79 | GRM2 (0.47) | ALDH1A1GAAKDM4EAPPMEN1 | |
| SCHEMBL28195991 | 0.79 | PSMB5 (0.50) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL27204402 | 0.77 | CYP2A6 (0.48) | ALDH1A1APPTSHRCYP2A6CYP2A13 | |
| SCHEMBL10111145 | 0.77 | ALDH1A1 (0.54) | ALDH1A1GAAAPPTSHRSNCA | |
| SCHEMBL10899140 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP2A6MEN1KMT2ARAB9A | |
| SCHEMBL14840562 | 0.76 | KDM4E (0.49) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-10-04 | — | — | US | claimed |
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | DHPS, COASY, PPIE | ALDH1A1 351/4885GAA 1593/4885KDM4E 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.