Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439295 | 1.00 | PSMB5 (0.46) | PSMB5MEN1MAPK1KMT2AMAPT | |
| SCHEMBL9472294 | 0.87 | MEN1 (0.47) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL27204402 | 0.82 | CYP2A6 (0.48) | MEN1MAPK1KMT2AMAPTLMNA | |
| SCHEMBL5444621 | 0.81 | MAOA (0.42) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5447779 | 0.81 | ALDH1A1 (0.49) | PSMB5MEN1MAPK1KMT2AMAPT | |
| SCHEMBL13891046 | 0.79 | MMP2 (0.49) | PNPLA2HDAC6 | |
| SCHEMBL3200553 | 0.77 | PTPN1 (0.42) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL11769391 | 0.76 | MEN1 (0.48) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL9789927 | 0.76 | CYP2A6 (0.73) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL27937014 | 0.76 | CYP2A6 (0.46) | MEN1MAPK1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-10-04 | — | — | US | claimed |
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232813-A1 | Substituted Cyclohexadienals - Syntheses and Applications | DHPS, COASY, PPIE | PSMB5 546/4885MEN1 2945/4885MAPK1 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.