SCHEMBL544809

SCHEMBL544809

O=Cc1cc(Br)cc(C=O)c1O

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 14/20 0.78
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PIM1 P11309 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4062201 0.88 ERN1 (0.69) ERN1CYP3A4TSHRTDP1PIM1
SCHEMBL2120180 0.88 ERN1 (1.00) ERN1CYP3A4TSHRTDP1
SCHEMBL29371317 0.88 ERN1 (1.00) ERN1CYP3A4TSHRTDP1
SCHEMBL30689083 0.88 ERN1 (0.69) ERN1CYP3A4TSHRTDP1PIM1
SCHEMBL29384871 0.84 ERN1 (0.64) ERN1
SCHEMBL411126 0.84 ERN1 (0.64) ERN1
SCHEMBL5642991 0.84 ERN1 (0.64) ERN1TDP1
SCHEMBL29743732 0.84 ERN1 (0.64) ERN1TDP1
SCHEMBL6679053 0.84 ERN1 (0.64) ERN1CYP3A4TSHRTDP1PIM1
SCHEMBL883382 0.84 ERN1 (0.64) ERN1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285844-B High-elastic polyurethane hot melt adhesive and preparation method thereof 浙江澳宇新材料科技有限公司 2023-08-18 CN claimed
CN-116459874-A Photosensitive metal complex film and preparation method and application thereof 天津理工大学 2023-07-21 CN claimed
CN-116285844-A High-elastic polyurethane hot melt adhesive and preparation method thereof 浙江澳宇新材料科技有限公司 2023-06-23 CN claimed
CN-112778286-B Multi-group compound with fluorescence specificity response to different anions and preparation method and application thereof 北京工业大学 2023-03-14 CN claimed
CN-113801100-B Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-05-06 CN claimed
CN-113845535-B Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-03-08 CN claimed
CN-113845535-A Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-28 CN claimed
CN-113801100-A Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-17 CN claimed
CN-112778286-A Multi-group compound with fluorescence specificity response to different anions and preparation method and application thereof 北京工业大学 2021-05-11 CN claimed
CN-119954759-A Benzopyran COX-2 inhibitor and application thereof 安炎达医药技术(广州)有限公司 2025-05-09 CN disclosed
CN-116459874-B Photosensitive metal complex film and preparation method and application thereof 天津理工大学 2025-02-07 CN disclosed
CN-116285844-B High-elastic polyurethane hot melt adhesive and preparation method thereof 浙江澳宇新材料科技有限公司 2023-08-18 CN disclosed
CN-116459874-A Photosensitive metal complex film and preparation method and application thereof 天津理工大学 2023-07-21 CN disclosed
CN-116285844-A High-elastic polyurethane hot melt adhesive and preparation method thereof 浙江澳宇新材料科技有限公司 2023-06-23 CN disclosed
EP-1481268-A2 NANOFILM AND MEMBRANE COMPOSITIONS Covalent Partners, LLC (US) 2004-12-01 EP disclosed
US-20040106741-A1 Nanofilm compositions with polymeric components COVALENT PARTNERS LLC 2004-06-03 US disclosed
US-20040034223-A1 Amphiphilic molecular modules and constructs based thereon COVALENT PARTNERS, LLC. 2004-02-19 US disclosed
US-20030199688-A1 Macrocyclic module compositions COVALENT PARTNERS, LLC 2003-10-23 US disclosed
WO-2003067286-A2 NANOFILM AND MEMBRANE COMPOSITIONS COVALENT PARTNERS, LLC (US) 2003-08-14 WO disclosed
WO-2003066646-A2 MACROCYCLIC MODULE COMPOSITIONS COVALENT PARTNERS, LLC (US) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199688-A1 Macrocyclic module compositions CYCS, IMMT, INTS9 ERN1 4465/4885CYP3A4 1409/4885TSHR 4517/4885
US-20040034223-A1 Amphiphilic molecular modules and constructs based thereon ANXA6, THEM6, ANXA5 ERN1 4768/4885CYP3A4 4804/4885TSHR 4398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.