Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667103 | 0.73 | LMNA (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL5448095 | 0.71 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL5694521 | 0.69 | ALDH1A1 (0.75) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL14862128 | 0.69 | NOTUM (0.51) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL27548796 | 0.68 | NPC1 (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL9016338 | 0.68 | CA12 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL12835098 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL9453927 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL5526949 | 0.68 | ABCC1 (0.63) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL28431651 | 0.68 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |