Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picolamine SCHEMBL11662843 | 0.86 | CHRNB2 (0.45) | KDM4EHTTALDH1A1GAANOTUM | |
| SCHEMBL27300735 | 0.83 | KDM4E (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL11836720 | 0.83 | KDM4E (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL965251 | 0.81 | NOTUM (0.51) | KDM4EHTTALDH1A1GAAMAPT | |
| SCHEMBL7667103 | 0.80 | LMNA (0.62) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3576501 | 0.77 | NOTUM (0.51) | KDM4EHTTALDH1A1GAAMAPT | |
| SCHEMBL8848450 | 0.77 | FAAH (0.64) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL427122 | 0.76 | NOTUM (0.50) | KDM4EHTTLMNAALDH1A1GAA | |
| SCHEMBL16295458 | 0.76 | NOTUM (0.50) | KDM4EHTTALDH1A1GAAMAPT | |
| SCHEMBL1577273 | 0.76 | NOTUM (0.50) | KDM4EHTTALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| US-4297342-A | USEFUL AS RODENTICIDES | ROHM AND HAAS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4233289-A | 3-Pyridylmethylthiocarbamates | ROHM AND HAAS COMPANY (US) | 1980-11-11 | — | — | US | disclosed |
| US-4156780-A | 3-Pyridylmethylthiocarbamates | ROHM AND HAAS COMPANY (US) | 1979-05-29 | — | — | US | disclosed |