SCHEMBL5448159

SCHEMBL5448159

CCCCCCCCCCCC(=O)NC(=S)Nc1cc(OC)ccc1OC

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
LMNA P02545 1/20 0.66
KMT2A Q03164 4/20 0.60
GAA P10253 2/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
ALOX12 P18054 1/20 0.57
POLB P06746 2/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
NPY1R P25929 1/20 0.54
NPY2R P49146 1/20 0.54
MEN1 O00255 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
KDM4E B2RXH2 1/20 0.53
CRHBP P24387 1/20 0.53
HTT P42858 1/20 0.53
CRHR2 Q13324 1/20 0.53
KCNH2 Q12809 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368156 0.88 GAA (0.76) ALDH1A1LMNAKMT2AGAATDP1
SCHEMBL17817424 0.88 GAA (0.76) ALDH1A1LMNAKMT2AGAATDP1
SCHEMBL5445850 0.82 CNR1 (0.65) ALDH1A1KMT2AL3MBTL1MAPTHPGD
SCHEMBL8708567 0.78 ALDH1A1 (0.69) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL5452848 0.77 ALDH1A1 (0.79) ALDH1A1LMNAKMT2AMAPTHPGD
SCHEMBL8918895 0.77 KMT2A (0.71) ALDH1A1LMNAKMT2AGAATDP1
SCHEMBL14338647 0.76 KMT2A (0.61) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL14338653 0.76 KMT2A (0.61) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL14338648 0.76 KMT2A (0.61) ALDH1A1KMT2AGAATDP1L3MBTL1
SCHEMBL14338660 0.76 KMT2A (0.61) ALDH1A1KMT2AGAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed