Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 11/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454644 | 0.92 | PDE10A (0.51) | DRD4DRD2CNR2CNR1PDE10A | |
| SCHEMBL5453968 | 0.88 | CNR2 (0.49) | DRD4DRD2CNR2CNR1PDE10A | |
| SCHEMBL5444434 | 0.87 | CNR2 (0.52) | DRD4DRD2CNR2PDE10A | |
| SCHEMBL5448700 | 0.87 | CNR2 (0.54) | CNR2CNR1PDE10ACXCR4 | |
| SCHEMBL5463014 | 0.86 | SCD (0.47) | CNR2CNR1PDE10ACXCR4 | |
| SCHEMBL5446468 | 0.86 | LMNA (0.48) | CNR2 | |
| SCHEMBL5454738 | 0.85 | CNR2 (0.50) | DRD4DRD2CNR2CNR1MEN1 | |
| SCHEMBL5449903 | 0.85 | CNR2 (0.45) | CNR2CNR1PDE10A | |
| SCHEMBL5452292 | 0.85 | CNR2 (0.46) | DRD4DRD2CNR2CNR1PDE10A | |
| SCHEMBL5451967 | 0.85 | CNR2 (0.50) | DRD4DRD2CNR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | DRD4 4022/4885DRD2 2688/4885CNR2 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.