Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485082 | 0.82 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL6476265 | 0.78 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL5798614 | 0.77 | JAK2 (0.31) | — | |
| SCHEMBL5441789 | 0.75 | — | — | |
| SCHEMBL6487409 | 0.74 | JAK1 (0.34) | — | |
| SCHEMBL5446225 | 0.64 | ATR (0.41) | — | |
| SCHEMBL6642545 | 0.63 | LPO (0.34) | — | |
| SCHEMBL1275546 | 0.62 | GABRA1 (0.40) | — | |
| SCHEMBL18268850 | 0.61 | RET (0.33) | — | |
| SCHEMBL13508575 | 0.61 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197510-A1 | Nitriles and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1724264-A1 | NITRILES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197510-A1 | Nitriles and medicinal compositions containing the same as the active ingredient | CTRL, NOS1, CPN1 | ADORA3 2870/4885ADRA1D 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.