Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.68 |
| ▸ | BACE1 | P56817 | 3/20 | 0.64 |
| ▸ | APP | P05067 | 3/20 | 0.61 |
| ▸ | ERN1 | O75460 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218542 | 0.87 | BACE1 (0.82) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3218566 | 0.87 | BACE1 (0.82) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31155862 | 0.87 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29565642 | 0.87 | BACE1 (0.82) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11971396 | 0.87 | GABRA3 (0.72) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11971397 | 0.87 | GABRA3 (0.72) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1405049 | 0.85 | GABRA3 (0.70) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31501090 | 0.85 | GABRA3 (0.70) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10321326 | 0.85 | GABRA3 (0.70) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1405050 | 0.85 | GABRA3 (0.70) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110589-B2 | Ectoparasiticide composition and a method for exterminating extoparasites | KYOYU AGRI CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090312378-A1 | ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES | YASHIMA SANGYO CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312378-A1 | ECTOPARASITICIDE COMPOSITION AND A METHOD FOR EXTERMINATING ECTOPARASITES | EPX, TYR, PPOX | MAPT 1101/4885ALDH1A1 2194/4885MEN1 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.