Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.64 |
| ▸ | AIP | O00170 | 1/20 | 0.63 |
| ▸ | SGTA | O43765 | 1/20 | 0.63 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.63 |
| ▸ | STIP1 | P31948 | 1/20 | 0.63 |
| ▸ | PPP5C | P53041 | 1/20 | 0.63 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.63 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.63 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453629 | 0.89 | PDE4B (0.65) | PDE4BPDE4DKDM4EMEN1KMT2A | |
| SCHEMBL3914715 | 0.83 | FLT3 (0.74) | PDE4BPDE4DKDM4EMEN1KMT2A | |
| SCHEMBL13159105 | 0.76 | RXFP1 (0.64) | PDE4BPDE4DKDM4EMEN1KMT2A | |
| SCHEMBL18177310 | 0.74 | MAPT (0.61) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL5451446 | 0.73 | AIP (0.71) | PDE4BPDE4DAIPSGTATOMM70 | |
| SCHEMBL5453282 | 0.73 | AIP (0.71) | PDE4BPDE4DAIPSGTATOMM70 | |
| SCHEMBL5460515 | 0.72 | AIP (0.69) | PDE4BPDE4DAIPSGTATOMM70 | |
| SCHEMBL1066142 | 0.72 | FLT3 (0.68) | PDE4BPDE4DAIPSGTATOMM70 | |
| SCHEMBL13159104 | 0.71 | NPC1 (0.60) | PDE4BPDE4DKDM4EMEN1KMT2A | |
| SCHEMBL8290414 | 0.70 | MEN1 (0.75) | KDM4EMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | PDE4B 1387/4885PDE4D 1518/4885AIP 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.