Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | FPR1 | P21462 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446699 | 0.89 | MEN1 (0.53) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL29835096 | 0.82 | HTT (0.74) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL5448323 | 0.81 | ENPP2 (0.49) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL4882118 | 0.80 | ENPP2 (0.57) | MEN1KMT2AUSP2CYP3A4CYP2C9 | |
| SCHEMBL4882902 | 0.78 | MAPT (0.64) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL4698864 | 0.78 | P2RX7 (0.55) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL5448123 | 0.76 | ENPP2 (0.42) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL5476310 | 0.76 | TSHR (0.42) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL29813896 | 0.75 | CYP3A4 (0.70) | MEN1KMT2AUSP2RECQLNPSR1 | |
| SCHEMBL833831 | 0.75 | CYP3A4 (0.73) | MEN1KMT2AUSP2RECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | ABBOTT LABORATORIES | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259920-A1 | P2X7, receptor antagonists and uses thereof | P2RX7, P2RX1, P2RX3 | MEN1 3501/4885KMT2A 4301/4885USP2 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.