Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698844 | 0.85 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL5452453 | 0.80 | KDM4E (0.47) | KMT2AKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2119530 | 0.80 | NPC1 (0.55) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL27919018 | 0.79 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28143597 | 0.79 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL7752287 | 0.79 | ADRB2 (0.55) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28144632 | 0.79 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL27883139 | 0.77 | KMT2A (0.50) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL10582027 | 0.77 | TSHR (0.52) | KMT2APOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL1829907 | 0.77 | PPARG (0.51) | KMT2AGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149440-B2 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-06 | — | — | US | disclosed |
| US-20070190160-A1 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190160-A1 | Nanoparticles for drug-delivery | EPCAM, TUBB1, ACTB | NR4A1 4121/4885NR4A2 3688/4885NR4A3 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.