Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450043 | 0.80 | NR4A1 (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10582027 | 0.77 | TSHR (0.52) | ALDH1A1HPGDKMT2AMEN1CYP1A2 | |
| SCHEMBL4354480 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5452455 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10559440 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5957199 | 0.71 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL1829907 | 0.71 | PPARG (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6940992 | 0.70 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL31240530 | 0.70 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL27647578 | 0.70 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149440-B2 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA (US) | 2015-10-06 | — | — | US | disclosed |
| US-20070190160-A1 | Nanoparticles for drug-delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-08-16 | — | — | US | disclosed |
| WO-2005020933-A2 | NANOPARTICLES FOR DRUG-DELIVERY | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190160-A1 | Nanoparticles for drug-delivery | EPCAM, TUBB1, ACTB | KDM4E 4213/4885ALDH1A1 897/4885HPGD 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.