Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450043 | 0.85 | NR4A1 (0.47) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL2119530 | 0.85 | NPC1 (0.55) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28654021 | 0.84 | ALDH1A1 (0.50) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL27919018 | 0.83 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL5925093 | 0.83 | NR4A1 (0.56) | NR4A1NR4A2NR4A3PPARGPPARA | |
| SCHEMBL7752287 | 0.83 | ADRB2 (0.55) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28143597 | 0.83 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28144632 | 0.83 | NPC1 (0.54) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL27883139 | 0.82 | KMT2A (0.50) | NR4A1NR4A2NR4A3ADRB2ADRB1 | |
| SCHEMBL28398051 | 0.80 | PPARG (0.53) | NR4A1NR4A2NR4A3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423211-B1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | KANEKA CORP (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2423211-A1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | Kaneka Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |