Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445578 | 0.82 | ALDH1A1 (0.58) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL5454001 | 0.80 | POLB (0.59) | RAB9ANPC1MAPK1ESR2SMN1; SMN2 | |
| SCHEMBL5449642 | 0.79 | RAB9A (0.60) | RAB9ANPC1MAPK1ESR2SMN1; SMN2 | |
| SCHEMBL5448122 | 0.77 | NPC1 (0.58) | RAB9ANPC1MAPK1ESR2SMN1; SMN2 | |
| SCHEMBL5450396 | 0.76 | ALDH1A1 (0.72) | RAB9ANPC1MAPK1SMN1; SMN2GAA | |
| SCHEMBL29661194 | 0.75 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL5445822 | 0.75 | RAB9A (0.73) | RAB9ANPC1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL12857742 | 0.75 | RAB9A (1.00) | RAB9ANPC1MAPK1ESR2SMN1; SMN2 | |
| SCHEMBL11364578 | 0.75 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL28033910 | 0.74 | MAPT (0.69) | RAB9ANPC1MAPK1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |