Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450048 | 0.80 | RAB9A (0.62) | POLBNPC1RAB9AMAPK1ESR2 | |
| SCHEMBL5446625 | 0.77 | SMN1; SMN2 (0.60) | POLBNPC1RAB9AKMT2AGAA | |
| SCHEMBL5448122 | 0.75 | NPC1 (0.58) | POLBNPC1RAB9AMAPK1ESR2 | |
| Fenfuram SCHEMBL748512 | 0.74 | MAPK1 (0.54) | POLBNPC1RAB9AMAPK1ESR2 | |
| SCHEMBL5455033 | 0.72 | NPC1 (0.60) | POLBNPC1RAB9AMAPK1ESR2 | |
| SCHEMBL5449642 | 0.72 | RAB9A (0.60) | POLBNPC1RAB9AMAPK1ESR2 | |
| SCHEMBL238548 | 0.72 | ALDH1A1 (0.66) | POLBNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL11606847 | 0.71 | POLB (0.86) | POLBNPC1RAB9AMAPK1ESR2 | |
| SCHEMBL5445865 | 0.70 | SMN1; SMN2 (0.57) | POLBNPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL5451777 | 0.70 | ALDH1A1 (0.60) | POLBNPC1RAB9AMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |