Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112688 | 0.93 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL4127114 | 0.92 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5463708 | 0.89 | CACNA1F (0.41) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5448669 | 0.88 | KDM4E (0.45) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL4106662 | 0.87 | CACNA1F (0.48) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5456955 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5449799 | 0.81 | NR3C2 (0.40) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5454384 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5447133 | 0.79 | CACNA1F (0.60) | ALDH1A1HSD17B10KDM4ENPSR1TSHR | |
| SCHEMBL5445083 | 0.79 | CACNA1F (0.58) | ALDH1A1HSD17B10KDM4ENPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | ALDH1A1 743/4885HSD17B10 247/4885KDM4E 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.