Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451953 | 0.93 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL4106662 | 0.85 | CACNA1F (0.48) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL5451633 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL5450116 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL7241522 | 0.82 | ADORA3 (0.55) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL8260388 | 0.78 | NR3C2 (0.47) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL4112688 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL4127114 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL5447133 | 0.77 | CACNA1F (0.60) | ALDH1A1KDM4EHSD17B10NPSR1TSHR | |
| SCHEMBL4118573 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | ALDH1A1 743/4885KDM4E 569/4885HSD17B10 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.