Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685407 | 0.87 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL28289966 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL2942285 | 0.77 | LIPG (0.48) | GABRA1GABRB2ALDH1A1LMNAKDM4E | |
| SCHEMBL7233310 | 0.76 | GABRA1 (0.61) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5136984 | 0.76 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL168974 | 0.75 | GABRA1 (0.79) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5824091 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| Hydrogen Peroxide SCHEMBL7819301 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| Hydrogen Peroxide SCHEMBL10784213 | 0.74 | GABRA1 (0.58) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| Boric Acid SCHEMBL8622423 | 0.74 | GABRA1 (0.63) | GABRA1GABRB2AKR1B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205427-B2 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | BOULDER SCIENTIFIC COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | ANTARES CAPITAL LP, AS AGENT | 2004-12-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | DDT, DUOX2, DYRK4 | GABRA1 1204/4885GABRB2 976/4885AKR1B1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.