Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 5/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL8987188 | 0.95 | ACHE (0.78) | ACHECA2CA9CA1LDHA | |
| Carbamic Acid SCHEMBL2472526 | 0.95 | — | — | |
| Carbamic Acid SCHEMBL2581200 | 0.90 | — | — | |
| Urea SCHEMBL3127972 | 0.90 | LMNA (0.60) | ACHECA2CA9CA1LDHA | |
| Carbamic Acid SCHEMBL28110069 | 0.90 | — | — | |
| Carbamic Acid SCHEMBL9174045 | 0.89 | ACHE (0.88) | ACHECA2CA9CA1LDHA | |
| Carbamic Acid SCHEMBL1356882 | 0.89 | — | — | |
| Carbamic Acid SCHEMBL16295670 | 0.84 | ACHE (0.78) | ACHECA2CA9CA1LDHA | |
| Carbamic Acid SCHEMBL3203837 | 0.84 | — | — | |
| Carbamic Acid SCHEMBL6258349 | 0.84 | ACHE (0.78) | ACHECA2CA9CA1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179861-B2 | Carbamate functional addition polymers and a method for their preparation | BASF CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| US-7138463-B2 | Carbamate functional addition polymers and a method for their preparation | BASF CORPORATION (US) | 2006-11-21 | — | — | US | disclosed |
| US-20050154163-A1 | Carbamate functional addition polymers and a method for their preparation | CAMPBELL DONALD (US) | 2005-07-14 | — | — | US | disclosed |
| US-20040186240-A1 | Carbamate functional addition polymers and a method for their preparation | CAMPBELL DONALD H (US) | 2004-09-23 | — | — | US | disclosed |
| WO-2004041873-A1 | CARBAMATE FUNCTIONAL ADDITION POLYMERS AND A METHOD FOR THEIR PREPARATION | BASF CORPORATION - GENERAL APPOINTMENT OF REPRESENTATIVE, ALLMAN, THOMAS Y., SENIOR VICE PRESIDENT, GENERAL COUNSEL (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087728-A1 | Carbamate functional addition polymers and a method for their preparation | BASF CORPORATION | 2004-05-06 | — | — | US | disclosed |