Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443991 | 0.89 | MAPK8 (0.40) | SMN1; SMN2HPGDKMT2AHTTMAPT | |
| SCHEMBL5440177 | 0.86 | HPGD (0.35) | HRH3L3MBTL1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5441177 | 0.85 | ADORA3 (0.40) | L3MBTL1SMN1; SMN2HPGDKMT2AHTT | |
| SCHEMBL5451001 | 0.84 | L3MBTL1 (0.37) | L3MBTL1SMN1; SMN2HPGDKMT2AHTT | |
| SCHEMBL5445127 | 0.82 | HPGD (0.34) | HRH3L3MBTL1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5446949 | 0.80 | HPGD (0.32) | HRH3L3MBTL1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5453316 | 0.80 | HPGD (0.32) | HRH3L3MBTL1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL5455618 | 0.78 | HPGD (0.33) | L3MBTL1SMN1; SMN2HPGDKMT2AHTT | |
| SCHEMBL6310356 | 0.78 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2HPGDKMT2AHTT | |
| SCHEMBL5439351 | 0.77 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2HPGDKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191395-A1 | Heterocyclic compounds having antifungal activity | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1717238-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191395-A1 | Heterocyclic compounds having antifungal activity | ERG28, MANBA, MAN2B1 | HRH3 3568/4885L3MBTL1 3180/4885SMN1; SMN2 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.