Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665741 | 0.81 | LMNA (0.41) | LMNAPYCR1KMT2AMAPTGAA | |
| SCHEMBL8205 | 0.80 | PDPK1 (0.43) | PYCR1PDPK1KDM1AAKR1B1NAAA | |
| SCHEMBL472482 | 0.80 | GABRA1 (0.50) | LMNAKMT2AMAPTGAAALOX12 | |
| SCHEMBL11223610 | 0.79 | LMNA (0.40) | LMNAPYCR1KMT2AMAPTGAA | |
| SCHEMBL12833031 | 0.79 | IDO1 (0.48) | LMNAKMT2AMEN1GABRA1GABRB2 | |
| SCHEMBL1311119 | 0.77 | PYCR1 (0.46) | LMNAPYCR1PDPK1KDM1AAKR1B1 | |
| SCHEMBL2095254 | 0.77 | PYCR1 (0.46) | PYCR1PDPK1KDM1AAKR1B1NAAA | |
| SCHEMBL8165898 | 0.76 | PYCR1 (0.44) | LMNAPYCR1KMT2AMAPTGAA | |
| SCHEMBL8173928 | 0.76 | LMNA (0.43) | LMNAPYCR1KMT2AMAPTGAA | |
| SCHEMBL9640862 | 0.76 | ESR1 (0.49) | KMT2AMAPTGAAMEN1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | LMNA 826/4885PYCR1 190/4885PDPK1 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.