Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445274 | 0.89 | DRD2 (0.44) | TP53KMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL5458572 | 0.89 | ALDH1A1 (0.54) | TP53KMT2AALDH1A1MEN1DRD2 | |
| SCHEMBL5451057 | 0.82 | MEN1 (0.55) | TP53KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL5753631 | 0.82 | DRD2 (0.53) | KMT2AKDM4EHDAC1HDAC6MEN1 | |
| SCHEMBL5454426 | 0.82 | MEN1 (0.61) | KMT2AKDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL5467983 | 0.81 | CYP3A4 (0.48) | TP53KMT2AALDH1A1MEN1DRD2 | |
| SCHEMBL5467644 | 0.81 | POLB (0.50) | KMT2AHDAC1HDAC6DRD2HTT | |
| SCHEMBL5461335 | 0.81 | DRD2 (0.52) | KMT2AKDM4EHDAC1HDAC6MEN1 | |
| SCHEMBL5454473 | 0.81 | CYP3A4 (0.48) | TP53KMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL5454599 | 0.80 | ALDH1A1 (0.46) | TP53KMT2AKDM4EALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | TP53 4865/4885KMT2A 2911/4885KDM4E 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.