Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445274 | 0.89 | DRD2 (0.44) | ALDH1A1KMT2ADRD2DRD4TP53 | |
| SCHEMBL5461488 | 0.86 | MAPT (0.53) | ALDH1A1KMT2ADRD2DRD4TP53 | |
| SCHEMBL5455428 | 0.81 | DRD2 (0.47) | ALDH1A1KMT2ADRD2DRD4HTT | |
| SCHEMBL5451078 | 0.80 | TP53 (0.54) | ALDH1A1KMT2ADRD2TP53KDM4E | |
| SCHEMBL5453456 | 0.80 | DRD2 (0.40) | ALDH1A1KMT2ADRD2DRD4HDAC1 | |
| SCHEMBL5460394 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2ADRD2DRD4KDM4E | |
| SCHEMBL5458663 | 0.79 | P2RX4 (0.44) | ALDH1A1DRD2DRD4TP53KDM4E | |
| SCHEMBL5456346 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL5448632 | 0.78 | TP53 (0.40) | ALDH1A1KMT2ATP53KDM4EHSD17B10 | |
| SCHEMBL5451758 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2ADRD2DRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | ALDH1A1 489/4885KMT2A 2911/4885DRD2 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.