Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 14/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410878 | 1.00 | PRPS1 (0.44) | PRPS1CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL14463856 | 0.90 | PRPS1 (0.42) | PRPS1CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL14411127 | 0.90 | CNR2 (0.47) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL5449208 | 0.90 | CNR2 (0.47) | CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL5449236 | 0.89 | PRPS1 (0.44) | PRPS1CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL14411139 | 0.89 | PRPS1 (0.44) | PRPS1CNR1CNR2OPRM1OPRD1 | |
| SCHEMBL14410888 | 0.87 | CNR2 (0.52) | CNR1CNR2 | |
| SCHEMBL14411897 | 0.87 | PRPS1 (0.43) | PRPS1CNR1OPRM1OPRD1HRH2 | |
| SCHEMBL5451564 | 0.87 | CNR2 (0.52) | CNR1CNR2 | |
| SCHEMBL5453912 | 0.87 | PRPS1 (0.43) | PRPS1CNR1OPRM1OPRD1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | PRPS1 4276/4885CNR1 65/4885CNR2 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.