Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | AKT2 | P31751 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452695 | 0.92 | AKT1 (0.54) | AKT1AKT2DPP4DPP8DPP9 | |
| SCHEMBL5348576 | 0.89 | AKT1 (0.65) | AKT1AKT2NPC1POLBRAB9A | |
| SCHEMBL5340819 | 0.86 | AKT1 (0.46) | AKT1AKT2DPP4DPP8DPP9 | |
| SCHEMBL5440820 | 0.84 | CNR1 (0.43) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4080087 | 0.77 | CNR1 (0.59) | DPP4DPP8DPP9MAPTNPC1 | |
| SCHEMBL4080145 | 0.76 | CNR1 (0.52) | DPP4DPP8DPP9MAPTNPC1 | |
| SCHEMBL4515129 | 0.75 | HSD17B10 (0.58) | DPP4DPP8DPP9MAPTNPC1 | |
| SCHEMBL5341021 | 0.75 | AKT1 (0.49) | AKT1AKT2DPP4DPP8DPP9 | |
| SCHEMBL5338476 | 0.74 | GABRA2 (0.48) | AKT1AKT2MAPTNPC1POLB | |
| SCHEMBL5343717 | 0.74 | GABRA2 (0.48) | AKT1AKT2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |