Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | AKT2 | P31751 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451404 | 0.92 | AKT1 (0.54) | AKT1AKT2CDC7DBF4CNR1 | |
| SCHEMBL5348576 | 0.89 | AKT1 (0.65) | AKT1AKT2NPC1POLBRAB9A | |
| SCHEMBL5340819 | 0.83 | AKT1 (0.46) | AKT1AKT2CDC7DBF4MAPT | |
| SCHEMBL5458454 | 0.78 | TP53 (0.44) | AKT1AKT2CDC7DBF4NPC1 | |
| SCHEMBL4085521 | 0.77 | CNR1 (0.61) | CDC7DBF4CNR1MAPTNPC1 | |
| SCHEMBL7045699 | 0.76 | CNR1 (0.62) | CDC7DBF4CNR1MAPTNPC1 | |
| SCHEMBL5440820 | 0.76 | CNR1 (0.43) | AKT1AKT2CNR1NPC1RAB9A | |
| SCHEMBL5343352 | 0.74 | AKT1 (0.49) | AKT1AKT2CDC7DBF4POLB | |
| SCHEMBL5338476 | 0.74 | GABRA2 (0.48) | AKT1AKT2MAPTNPC1POLB | |
| SCHEMBL5343717 | 0.74 | GABRA2 (0.48) | AKT1AKT2NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |