Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462247 | 0.81 | PLK1 (0.67) | PLK1NPC1RAB9AKMT2A | |
| SCHEMBL5454023 | 0.73 | EPHX1 (0.49) | NPC1RAB9AKMT2A | |
| SCHEMBL5453192 | 0.73 | EPHX1 (0.65) | NPC1RAB9AKMT2A | |
| SCHEMBL11054164 | 0.72 | GAA (0.50) | PLK1KMT2A | |
| SCHEMBL11364500 | 0.72 | EPHX1 (0.57) | KMT2A | |
| SCHEMBL17582498 | 0.72 | PLK1 (0.56) | PLK1NPC1RAB9A | |
| SCHEMBL11158773 | 0.71 | PLK1 (0.55) | PLK1NPC1RAB9AKMT2A | |
| SCHEMBL5443490 | 0.71 | ALDH1A1 (0.57) | NPC1RAB9AKMT2A | |
| SCHEMBL5455257 | 0.71 | GAA (0.58) | — | |
| SCHEMBL5455082 | 0.70 | ALDH1A1 (0.53) | NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |