Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453192 | 0.86 | EPHX1 (0.65) | EPHX1ALDH1A1KDM4ERAB9ANPSR1 | |
| SCHEMBL5455082 | 0.82 | ALDH1A1 (0.53) | EPHX1ALDH1A1KDM4ERAB9ANPSR1 | |
| SCHEMBL5459767 | 0.82 | ALDH1A1 (0.59) | EPHX1ALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL5464193 | 0.82 | ALDH1A1 (0.59) | EPHX1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL12768389 | 0.78 | ALDH1A1 (0.71) | EPHX1ALDH1A1RAB9ANPSR1NPC1 | |
| SCHEMBL16358841 | 0.77 | KMT2A (0.70) | EPHX1ALDH1A1RAB9ANPSR1NPC1 | |
| SCHEMBL5451532 | 0.73 | PLK1 (0.47) | RAB9ANPC1KMT2A | |
| SCHEMBL14095975 | 0.73 | SIRT2 (0.60) | EPHX1ALDH1A1KDM4ERAB9ANPSR1 | |
| SCHEMBL5450412 | 0.73 | MAPT (0.43) | EPHX1ALDH1A1KDM4ERAB9ANPSR1 | |
| SCHEMBL5455033 | 0.72 | NPC1 (0.60) | ALDH1A1KDM4ERAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |