Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459767 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTEPHX1LMNAKDM4E | |
| SCHEMBL5454023 | 0.82 | EPHX1 (0.49) | ALDH1A1MEN1KMT2AEPHX1NPC1 | |
| SCHEMBL5453192 | 0.82 | EPHX1 (0.65) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL28945218 | 0.82 | EPHX1 (0.73) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL14096413 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL5464193 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| Hydrochloric Acid SCHEMBL3724823 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| Hydrochloric Acid SCHEMBL3724826 | 0.78 | PTGS1 (0.71) | ALDH1A1MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL5450412 | 0.78 | MAPT (0.43) | ALDH1A1MEN1MAPTKMT2AEPHX2 | |
| SCHEMBL3039438 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AEPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |