Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084667 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL30557461 | 0.85 | MEN1 (0.77) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL9453941 | 0.85 | MEN1 (0.77) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL17933242 | 0.81 | ALDH1A1 (0.66) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL9124869 | 0.81 | ALDH1A1 (0.86) | HPGDALDH1A1LMNAHTTPOLB | |
| SCHEMBL11674611 | 0.80 | KMT2A (0.75) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL11839367 | 0.80 | KMT2A (0.65) | SMN1; SMN2HPGDALDH1A1HTTPOLB | |
| SCHEMBL28807981 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2HPGDALDH1A1LMNAHTT | |
| SCHEMBL1275764 | 0.80 | KMT2A (0.72) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| SCHEMBL26485866 | 0.79 | LMNA (0.69) | SMN1; SMN2HPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368282-A | Method for synthesizing 1, 3-disubstituted thiourea in aqueous phase | 吉安宏达秋科技有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-115368282-A | Method for synthesizing 1, 3-disubstituted thiourea in aqueous phase | 吉安宏达秋科技有限公司 | 2022-11-22 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |