Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PRF1 | P14222 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167942 | 0.85 | FFAR1 (0.47) | FFAR1POLBPPARGMAPTMPC2 | |
| SCHEMBL5451781 | 0.82 | HPGD (0.54) | FFAR1HPGDTP53POLBPPARG | |
| SCHEMBL5167615 | 0.80 | FFAR1 (0.51) | FFAR1PPARGMAPTKDM4ECYP2C9 | |
| SCHEMBL5167756 | 0.77 | FFAR1 (0.55) | FFAR1PRF1PPARGMAPTMAOA | |
| SCHEMBL28992956 | 0.76 | PRF1 (0.48) | PRF1HPGDTP53POLBMAPT | |
| SCHEMBL1749935 | 0.76 | FFAR1 (0.54) | FFAR1PPARGMAPTCYP2C9MAOA | |
| SCHEMBL1751600 | 0.75 | FFAR1 (0.51) | FFAR1PPARGMAOACISD1 | |
| SCHEMBL1750394 | 0.74 | FFAR1 (0.46) | FFAR1KDM4EMAOACISD1 | |
| SCHEMBL1750799 | 0.73 | FFAR1 (0.49) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL1750798 | 0.73 | FFAR1 (0.49) | FFAR1PPARGMAPTMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078175-A1 | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof | L'OREAL (FR) | 2007-04-05 | — | — | US | claimed |
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | L'OREAL (FR) | 2007-04-05 | — | — | US | claimed |
| US-20070078175-A1 | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
| US-20070078175-A1 | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
| US-20070078175-A1 | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | L'OREAL (FR) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077215-A1 | Administration of phenylfurymethylthiazolidine-2,4-dione or phenylthienymethylthiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratinous substances and/or limiting their depigmentation and/or their whitening | TYR, KRT18, MITF | FFAR1 2943/4885PRF1 2218/4885HPGD 120/4885 |
| US-20070078175-A1 | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof | KRT18, NGF, FGF1 | FFAR1 2463/4885PRF1 1574/4885HPGD 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.