Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 9/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5455794 | 0.99 | CYP51A1 (0.46) | CYP51A1ALDH1A1HTTMC4RMC5R | |
| SCHEMBL5195017 | 0.92 | CYP51A1 (0.45) | CYP51A1ALDH1A1HTTAVPR1ACALCRL | |
| Hydrochloric Acid SCHEMBL5452099 | 0.89 | ALDH1A1 (0.39) | CYP51A1ALDH1A1HTTMC4RMC5R | |
| SCHEMBL5199301 | 0.88 | ALDH1A1 (0.47) | CYP51A1ALDH1A1HTTCACNA1B | |
| SCHEMBL5444005 | 0.83 | MC4R (0.42) | CYP51A1MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL5458137 | 0.82 | MC4R (0.42) | CYP51A1MC4RMC5RMC3RMC1R | |
| SCHEMBL5454784 | 0.81 | MC4R (0.46) | CYP51A1MC4RMC5RMC3RMC1R | |
| SCHEMBL5461302 | 0.80 | MC4R (0.43) | CYP51A1MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL5449626 | 0.80 | MC4R (0.43) | CYP51A1MC4RMC5RMC3RMC1R | |
| SCHEMBL5452961 | 0.79 | ALDH1A1 (0.44) | CYP51A1ALDH1A1HTTMC4RAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | CYP51A1 690/4885ALDH1A1 344/4885HTT 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.