Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451880 | 0.92 | CYP51A1 (0.47) | CYP51A1ALDH1A1HTTCACNA1BAVPR1A | |
| Hydrochloric Acid SCHEMBL5455794 | 0.91 | CYP51A1 (0.46) | CYP51A1ALDH1A1HTTCACNA1BAVPR1A | |
| SCHEMBL5199301 | 0.90 | ALDH1A1 (0.47) | CYP51A1ALDH1A1HTTCACNA1BKMT2A | |
| SCHEMBL5370825 | 0.83 | MC4R (0.40) | CYP51A1ALDH1A1HTTCACNA1BKMT2A | |
| SCHEMBL5197965 | 0.81 | MC4R (0.44) | CYP51A1 | |
| Hydrochloric Acid SCHEMBL5452099 | 0.81 | ALDH1A1 (0.39) | CYP51A1ALDH1A1HTTAVPR1ATSHR | |
| SCHEMBL5197473 | 0.80 | MC4R (0.42) | CYP51A1 | |
| SCHEMBL5197261 | 0.80 | TRPM8 (0.48) | ALDH1A1POLBHRH3CHRM2CHRM3 | |
| SCHEMBL5452961 | 0.79 | ALDH1A1 (0.44) | CYP51A1ALDH1A1HTTCACNA1BAVPR1A | |
| SCHEMBL5452964 | 0.79 | ALDH1A1 (0.44) | CYP51A1ALDH1A1HTTCACNA1BAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |