Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536616 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CPB1KMT2AKDM4E | |
| Phthalic Acid SCHEMBL22471697 | 0.89 | ALDH1A1 (0.64) | ALDH1A1ALOX15CPB1KMT2AKDM4E | |
| SCHEMBL5462752 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15CPB1KDM4ESMN1; SMN2 | |
| SCHEMBL5451947 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15CPB1KMT2AKDM4E | |
| SCHEMBL3027381 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15CPB1KMT2AKDM4E | |
| SCHEMBL3918618 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4ESMN1; SMN2HTT | |
| SCHEMBL8260835 | 0.79 | ACHE (0.53) | ALDH1A1CPB1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL13176096 | 0.79 | ACHE (0.53) | ALDH1A1CPB1KMT2AKDM4ESMN1; SMN2 | |
| Phthalic Acid SCHEMBL23275565 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ALOX15KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8536684 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |