Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.60 |
| ▸ | CDC42 | P60953 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459631 | 0.85 | PRMT5 (0.82) | PRMT5CDC42GAACASP6SIRT1 | |
| SCHEMBL12922444 | 0.78 | PRMT5 (0.89) | PRMT5CDC42ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL4147497 | 0.78 | CYP2D6 (0.74) | CDC42ALOX15MAPTSMN1; SMN2MEN1 | |
| SCHEMBL31497463 | 0.77 | PRMT5 (0.57) | PRMT5CDC42ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL21998617 | 0.77 | PRMT5 (0.57) | PRMT5CDC42GAACASP6SIRT1 | |
| SCHEMBL24863190 | 0.76 | CDC42 (0.77) | PRMT5CDC42ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL15167010 | 0.76 | CDC42 (0.77) | PRMT5CDC42ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL13702966 | 0.75 | PRMT5 (1.00) | PRMT5CDC42GAACASP6SIRT1 | |
| SCHEMBL16433477 | 0.75 | ALOX15 (0.71) | ALOX15MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21996536 | 0.74 | GAA (0.67) | PRMT5CDC42ALOX15MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | CHIRON CORPORATION | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276009-A1 | Compositions and Methods for Viral Inhibition | MAVS, SARS1, ZC3HAV1 | PRMT5 1060/4885CDC42 1241/4885ALOX15 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.