SCHEMBL5452024

SCHEMBL5452024

CCCCC1CNC(=O)O1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
MAOA P21397 1/20 0.45
SLC6A2 P23975 1/20 0.45
CYP1A2 P05177 2/20 0.44
PKM P14618 2/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
USP2 O75604 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GRM2 Q14416 2/20 0.41
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PPARG P37231 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322761 0.92 CYP1A2 (0.54) LMNAMAOASLC6A2CYP1A2PKM
SCHEMBL2830202 0.92 CYP1A2 (0.54) LMNAMAOASLC6A2CYP1A2PKM
SCHEMBL9322994 0.92 CYP1A2 (0.54) LMNAMAOASLC6A2CYP1A2PKM
SCHEMBL5450456 0.90
SCHEMBL2366099 0.81
SCHEMBL2281276 0.81
Hexane SCHEMBL17769241 0.81 PTPN1 (0.43) LMNAMAOASLC6A2CYP1A2PKM
SCHEMBL25051616 0.79 LMNA (0.42) LMNAMAOASLC6A2CYP1A2PKM
SCHEMBL14731300 0.79
SCHEMBL2033238 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070129578-A1 Method for the production of 2,2'-dihydroxybiphenyls BASF AKTIENGESELLSCHAFT (DE) 2007-06-07 US disclosed
EP-1682473-A1 METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS BASF Aktiengesellschaft (DE) 2006-07-26 EP disclosed
WO-2005042454-A1 METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS BASF AKTIENGESELLSCHAFT (DE) 2005-05-12 WO disclosed
US-4058462-A System for sustained release of phenolic material from porous granules of insoluble polymeric phenolic complexes GAF CORPORATION (US) 1977-11-15 US disclosed
US-4009039-A Heat developable light-sensitive oxazoline containing element FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed
US-3985540-A Metal complexes of hydroxyquinoline and polymeric porous granules GAF CORPORATION (US) 1976-10-12 US disclosed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129578-A1 Method for the production of 2,2'-dihydroxybiphenyls HAO2, DAO, DDO LMNA 591/4885MAOA 845/4885SLC6A2 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.